Health Buzz: New Anti-Clot Drug Could Help Heart Patients

New Anti-Clot Drug Shows Promise for Heart Patients

A new blood thinner could help prevent strokes among people with an irregular heartbeat. Patients with atrial fibrillation —who commonly experience strokes due to blood clots—typically take warfarin, a drug that requires strict supervision, since food and other medications can interfere with it. But researchers say a newer drug called rivaroxaban is as effective as warfarin, without the need for such close monitoring. The findings, based on a trial of more than 14,000 patients who took either warfarin or rivaroxaban, appear today in the New England Journal of Medicine . Though the new drug was approved last month to prevent clots in patients undergoing knee or hip replacement surgery, it hasn't yet been OK'd as an anti-stroke drug for people with atrial fibrillation (it's expected to be green-lighted in September). Rivaroxaban "will be game-changing for all of us that treat atrial fibrillation," Kousik Krishnan, an associate professor of medicine at Rush University Medical Center in Chicago, told HealthDay .

Drug Brain Damage - News


Meningitis Victims' Families Receive Settlement from a Drug Trial Gone Bad
Meningitis Victims' Families Receive Settlement from a Drug Trial Gone Bad

Other children who participated in the study suffered blindness, deafness and brain damage. In total, 547 families sued, although Pfizer said that only 200 children had been given the drugs. A Pfizer spokesman told the Times on Thursday that meningitis



Health Buzz: New Anti-Clot Drug Could Help Heart Patients

Minimizing the time between the onset of a stroke and the start of stroke treatment is critical for surviving the brain attack and minimizing the resulting brain injury. The key is to immediately get to the emergency room for a brain scan to detect



Alzheimer's drug tests in six years, Lancaster researcher says
Alzheimer's drug tests in six years, Lancaster researcher says

The disease affects 750000 people in the UK. The drug would stop the disease before it caused irreversible brain damage. "When the disease is diagnosed, the damage is already done," Prof David Allsop said. "We can now now detect the disease with quite



Jury acquits over cue incident

A jury has acquitted a prisoner who gave a fellow inmate brain damage with a pool cue, but the verdict does not mean freedom for Joseph Warren Lepper. He went back to jail afterwards to continue serving his 10-year rape sentence.



Stroke drug could reduce brain damage 12 hours later
Stroke drug could reduce brain damage 12 hours later

Brain damage after stroke could be limited by administering a drug within 12 hours of the attack, more than twice as long as current treatments, scientists have claimed. By Nick Collins, Science Correspondent A naturally occurring substance which slows




Cholesterol Lowering Drugs may lead to Brain Damage | Biomedical ...

About Cholesterol

Cholesterol has a bad reputation in this country and is well-known for causing atherosclerosis through plaque formation in arteries. According to the American Heart Association , over 100 million American adults have high cholesterol values of 200 mg/dL and up. Although too much cholesterol is never good, there are different types of cholesterol and some of it is naturally produced in our body as well.

“Good” Cholesterol aka HDL (high-density lipoprotein) – A healthy level of HDL can prevent against heart attacks and strokes, while too low of an HDL level (40 mg/dL) may lead to an increase in risk of heart disease. Healthy HDL levels can be maintained by regular exercise and reducing trans fats.

“Bad” Cholesterol aka LDL (low-density lipoprotein) – LDL is the cholesterol that gives all cholesterols a bad reputation. Increased levels of LDL adhere to the lumen of blood vessels and can cause blockages in the arteries, leading to a heart attack or stroke. LDL is produced naturally by the body and can be genetically inherited as well. Healthy LDL levels can be maintained by reducing saturated fat and trans fat intake and it’s very common for doctors to prescribe medications to lower LDL blood cholesterol.

How Cholesterol Affects the Brain

Although lowering LDL cholesterol through medications like Lipitor and Trilipix are good for the heart, they may have negative impacts on the brain.  These drugs contain Statin , which are HMG-CoA reductase inhibitors, and are very commonly prescribed cholesterol-lowering drugs.  The human brain contains about one fourth of the body’s total cholesterol and utilizes it to form neural connections that relate to memory and learning. Cholesterol helps form the myelin sheath around neurons, which allows for signals to jump between Schwann cells junctions.

Dr. Matthew Muldoon from the University of Pittsburgh researched deeper into the connection bewteen LDL lowering drugs and the human brain. He found several FDA complaints from cholesterol-lowering drug users claiming “memory loss, fuzzy thinking, and learning difficulties”.  Dr. Muldoon began a couple of studies with patients who had high cholesterol levels and found that the groups taking the LDL lowering medications had common complaints of memory issues. In order to verify his theories, the patients who suffered from memory and learning impairment from LDL lowering drugs were given placebos and over 50% of them claimed that their memory and learning symptoms improved significantly when given the placebos rather than the LDL lower drugs. Despite Dr. Muldoon’s research, many scientists still believe that the link between these LDL lowering medications and memory/learning impairment are very rare and suggest that the cognitive side effects can be cause by numerous other factors such as age, sugar levels, and genetics.


Twitter

Deepak I don't think any drug that can cause brain damage, failing kidneys, hardening arteries, pain, and suffering should be made available


Frank-N-Furter I must have brain damage. Woman is holding an empty coffee cup, tells me she's going for a drug test. First words out of my mouth?


chris murphy Cop Standen blamed innocent man for his own drug imports.Gaoled,bashed,brain damage,lost all.Now known innocent.Will hear lot about him


Dr. Nugz Brain damage, marijuana leads court to declare attacker not responsible: Neighbours of Vincenzo Pizzi, 48, were ...


destiny pendarvis The drug facts on our tooth paste says dont swallow but, why is fluoride in our water? Causes cancer, brain damage, an a slue of otha shyt!


Drug Brain Damage - Bookshelf

Addiction and brain damage

Addiction and brain damage

PREFACE Alcoholism and drug addiction are presenting serious problems in many parts of ... However, the nature of the brain damage, and the reasons why some ...

Brain injury medicine, principles and practice

Brain injury medicine, principles and practice

Recovery of function after brain damage: Severe and chronic disruption by ... Randomised study of antiepileptic drug withdrawal in patients in remission. ...

Traumatic brain injury, rehabilitative treatment and case management

Traumatic brain injury, rehabilitative treatment and case management

... function following brain injury, though this is reversible upon drug ... Even if diazepam is administered only for the first 7 days after brain damage, ...

Drug injury, liability, analysis, and prevention

Drug injury, liability, analysis, and prevention

30.3 Case Reports: Opiate Toxicity Causing Respiratory Arrest, Brain Damage, and Death Several case reports follow that discuss the clinical course, drug ...

Health Psychology, An Introduction to Behavior and Health

Health Psychology, An Introduction to Behavior and Health

Brain Damage Is Not a Common Risk of Drug Use (Lápez-Moreno et al., 2008). That is, drugs seem to activate the brain circuits that underlie re- ward. ...

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Long-term impact of drug use - Brain damage - Worldnews.com
Sydney: A new research on ecstasy, ice and speed users in Australia has uncovered tell-tale signs of brain damage. The study adds to concerns over the long-term ...

Evidence of Neuroleptic Drug-Induced Brain Damage
Evidence of Neuroleptic Drug-Induced Brain Damage in Patients: ... The author sought to discover whether brain damage could be an important contributory cause of TD. ...

Why drugs cause brain damage | NewsOK.com
... commercial that showed an egg cracked into a hot skillet with the message "This is your brain on drugs?" The egg represented a brain frying from drugs. ...

Ecstasy and the Brain | Drug Independence | Brain damage ...
Damages done by MDMA, Ecstasy, to the brain ... We now know that brain damage is still present in monkeys seven years after discontinuing the drug," Dr. Ricaurte says. ...

Will Years of Heavy Drinking Cause Brain Damage?
All of the nations best drug treatment centers and rehabs are listed. ... Will Years of Heavy Drinking Cause Brain Damage? The beer belly and a life of morning ...